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The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab)

The Evolution of Bacteria on a “Mega-Plate” Petri Dish (Kishony Lab)

Harvard Medical School
6 HN recommenders · discussed 2016–2026
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About this video

A two-minute time-lapse from the Kishony Lab showing bacteria spreading across a giant petri dish with increasing antibiotic doses, evolving resistance as they go.

Why it appears in the archive

HN links it as a visually striking demonstration of evolution and antibiotic resistance happening in days.

AI-generated summary and labels from the source dataset; verify important details against the video. Source & credits.

From the Hacker News discussion

lossolo · 2016-09 · strong rec

This is an amazing video[1] from Harvard Medical School released couple of days ago showing evolution of bacteria that evolve in 10 days to become resistant to antibiotics. [1] [VIDEO]

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robocat · 2019-07 · strong rec

> Why do you think the strongest of the strong bacteria are found in hospitals? I presume you mean strong against antibiotics and sterilisation. The evolved bacteria are likely weaker along other dimensions (that are less important for survival in a hospital setting). Some evolution is compromises, improving X has cost Y. Aside: the mega-plate video is an unbelievably good demonstration of bacterial evolution: [VIDEO] especially note the tree at the end showing how many different mutations evolved.

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Retric · 2016-09 · rec

The video shows mutations in real time as bacteria grow or fail to grow in various places. [VIDEO] It's more a demonstration than experiment, but visually it's just really striking.

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sengork · 2017-01 · rec

For those that would like to visualise how the bacteria vs anitbiotics evolve in an experiment over 11 days, have a look at this video from Harvard: [VIDEO]

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ramgorur · 2018-03 · rec

Harvard medical school did a similar experiment on fast evolution of bacterial resistance to antibiotics on a petri-dish. It also clearly shows the lineage of evolution. Very interesting. [VIDEO]

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idiocrat · 2023-01 · rec

Strengthens your immune system. Without exposure (playing in mud, touching other people), we are only weaker. Bio life is really complicated. Sterilization works well only to a certain degree, before becoming damaging, e.g. causing resistance. Somewhat related, here is an interesting visualization of bacteria developing resistance to antibiotics. [VIDEO]

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lmilcin · 2019-01 · reference

It is absolutely nowhere near evolutionary adaptive capacity. Life will not end and the world will still be there. Life's evolutionary adaptive capacity is stagerring! Just take a look at the experiment where it barely stretches muscles: [VIDEO] What I understand they mean is "Life as we know it" defined as large animals and familiar plants roughly in places where we are used to seeing them. We are looking at life with our antropocentric point of view and we basically want familiar stuff to stay the same and we don't want unfamiliar stuff to show up. We don't want things to change and that's why potential large shift in how life presents itself may be caulled as "end of the world" event, but it is not. Life doesn't care whether oceans are clean or polluted, hot or cold. It WILL adapt some way or another even if all crustaceans and fish will die because they can't adapt quickly enough to lowering pH. We should care not because life is at danger but because we are at danger. Life as we know it is a machine that supports us, let's us grow food and provides air and water and soil and climate that we need. Humans will survive for sure in one way or another even if the temperature rises by 20 degrees but what kind of life will it be and how much suffering for those that can't deal with it?

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estebank · 2020-10 · reference

The mitigations are effective in slowing the spread (to varying degrees, due to a multitude of factors), which in turn slow down the rate of mutation. In any case, I would expect the dispersion of the virus to follow a pattern similar to [VIDEO]

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